Urocortin 2 analogs and uses thereof
US9572866B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 2015 |
| Grant date | Feb 21, 2017 |
| Priority date | — |
| Expiry date | Jul 17, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are polypeptides that are analogs of urocortin 2 that have pharmacological activity similar to urocortin 2 but have improved water solubility compared to urocortin 2, and pharmaceutical compositions of the polypeptides of the present invention. Also disclosed are polynucleotides encoding the polypeptides, and methods of treating pathophysiological states employing pharmaceutical compositions of the polypeptides and polynucleotides of the present invention. In addition, disclosed are vectors and host cells that include a nucleic acid encoding a polypeptide of the present invention, and kits that include pharmaceutical compositions of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.