Synthesis of intermediates in the preparation of ALK inhibitor
US9573932B2 · kind B2 · utility
3Cited by
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13Claims
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Inventor
Key dates
| Filing date | Mar 2, 2015 |
| Grant date | Feb 21, 2017 |
| Priority date | — |
| Expiry date | Mar 2, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure provides a method for preparing a compound of formula XVII, comprising: (1) contacting a compound of formula XIV with a compound of formula 3 to obtain a compound of formula 2; and (2) contacting the compound of formula 2 with a compound of formula 4 to obtain a compound of formula XVII. The method is low toxicity, cheap, easy to get, environmentally and friendly, and is economical and industrially applicable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.