Therapeutic hydroxypyridinones, hydroxypyrimidinones and hydroxypyridazinones

US9573938B2 · kind B2 · utility

Assignee

• Rutgers, the State University of New Jersey · US

Inventors

• Edmond J. LaVoie · Princeton Junction, US
• Joseph David Bauman · New Brunswick, US
• Ajit Parhi · New Brunswick, US
• Hye Yeon Sagong · New Brunswick, US
• Disha Patel · New Brunswick, US
• Eddy Arnold · New Brunswick, US
• Kalyan Das · Edison, US
• Suyambu Kesava Vijayan · New Brunswick, US

Key dates

• Filing date: Sep 11, 2013
• Grant date: Feb 21, 2017
• Expiry date: Sep 11, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.