Patent · US Active

Chimeric antigen receptor compositions

US9574014B2 · kind B2 · utility

35Cited by
2References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 16, 2016
Grant dateFeb 21, 2017
Priority date—
Expiry dateMay 16, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/70
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided herein are compositions which exhibit novel diagnostic capabilities and allow to rapidly add functionality to adoptive immunotherapy. The compositions include isolated nucleic acids encoding proteins including antibody regions capable of binding compounds including a peptidyl moiety (e.g., a meditope). The recombinant proteins provided herein are useful, inter alia, for a broad variety of therapeutic and diagnostic purposes. For example, the recombinant proteins provided herein including embodiments thereof may be used as non-invasive means to characterize chimeric antigen receptor (CAR) T cells before and/or during treatment of diseases (e.g., cancer).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.