Methods and apparatus for independent control of product and reactant concentrations
US9574167B2 · kind B2 · utility
7Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 14, 2014 |
| Grant date | Feb 21, 2017 |
| Priority date | — |
| Expiry date | Jul 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M47/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.