MicroRNA compounds and methods for modulating miR-122
US9574194B2 · kind B2 · utility
5Cited by
16References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 29, 2016 |
| Grant date | Feb 21, 2017 |
| Priority date | — |
| Expiry date | Feb 29, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions and methods for the inhibition of miR-122 activity. The compositions have certain nucleoside modifications that yield potent inhibitors of miR-122 activity. The compounds may comprise conjugates to facilitate delivery to the liver. The compositions may be administered to subjects infected with hepatitis C virus, as a treatment for hepatitis C virus and related conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.