Synthesis of chiral 2-(1H-indazol-6-yl)-spiro[cyclopropane-1,3′-indolin]-2′-ones
US9579327B2 · kind B2 · utility
5Cited by
11References
16Claims
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Key dates
| Filing date | Dec 23, 2014 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Dec 23, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A):or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.