Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss
US9579347B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 4, 2013 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Oct 4, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA23V2002/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods for enhancing the efficacy of epigallocatechin gallate (“EGCg”) in mitigating skeletal muscle loss in a subject. Providing EGCg to a subject in a nutritional composition reduces muscle protein degradation, thereby mitigating skeletal muscle loss in the subject. The combination of EGCg with zinc in a nutritional composition enhances the mitigating effect that EGCg has on muscle loss. Specifically, when used in combination, a nutritional composition containing both EGCg and zinc requires less EGCg to obtain the same mitigating effect that occurs in the same nutritional composition containing EGCg but no zinc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.