Indazole compounds as kinase inhibitors and method of treating cancer with same
US9580390B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Oct 12, 2012 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Apr 23, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present teaching provide indazole compounds represented by Structural Formulae (I) or (I′) or a pharmaceutically acceptable salt thereof. Also described are pharmaceutical compositions and methods of use thereof as protein kinase inhibitors, such as TTK protein kinase, polo-like kinase 4 (PLK4) and Aurora kinases having anticancer activity against breast cancer cells, colon cancer cells, and ovarian cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.