Polymorphic form of sodium hyodeoxycholate (NaHDC) and its preparation process
US9580458B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Oct 2, 2014 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Oct 2, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The object of the present invention is a new anhydrous polymorphic crystalline form of sodium hyodeoxycholate (NaHDC) named as form II (FII) and the process for preparing it. Such a process makes it possible to obtain sodium hyodeoxycholate in the anhydrous polymorphic form II (FII), with high chemical and polymorphic purity. The invention also describes the anhydrous polymorphic crystalline forms of NaHDC named as form I (FI) and form III (Fill), the hydrated forms of NaHDC named as SI and SII, crystalline forms of NaHDC, respectively hydrated with four and eight water molecules and the amorphous form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.