Method for purifying active polypeptides or immunoconjugates
US9580461B2 · kind B2 · utility
10Cited by
2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 27, 2011 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Apr 4, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.