Methods of using compositions comprising variants and fusions of FGF19 polypeptides for treatment of diabetes
US9580483B2 · kind B2 · utility
36Cited by
55References
120Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 2015 |
| Grant date | Feb 28, 2017 |
| Priority date | — |
| Expiry date | Jul 13, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/66
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.