Noninvasive methods for determining the pressure gradient across a heart valve without using velocity data at the valve orifice
US9585568B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Sep 11, 2011 |
| Grant date | Mar 7, 2017 |
| Priority date | — |
| Expiry date | Jul 6, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H30/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Embodiments presented herein provide apparatus and methods for imaging-assisted determination of pressure gradient of blood flow across a valve orifice in a cardiovascular circuit without the use of velocity data measured at the valve orifice. An embodiment of the methods comprise creating an image of a valve orifice, creating a planimeter slice from the image of the valve orifice including a trace of the perimeter of the valve orifice, determining the valve orifice area by determining the area contained within the trace, determining the instantaneous flow rate through the valve orifice based on bulk flow data away from the valve, and determining the instantaneous pressure gradient across the valve orifice from the valve orifice area and the instantaneous flow rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.