Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith

US9585892B2 · kind B2 · utility

Assignee

• AMBIT BIOSCIENCES CORP. · US

Inventors

• Shripad S. Bhagwat · San Diego, US
• Wei Lai · West Lafayette, US
• Stephan D. Parent · West Lafayette, US
• Melanie Janelle Bevill · West Lafayette, US
• Alan Schwartz · Carlsbad, US
• Valeriya Smolenskaya · West Lafayette, US

Key dates

• Filing date: Oct 7, 2014
• Grant date: Mar 7, 2017
• Expiry date: Oct 7, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed.