Polypeptide hydrogels and uses related thereto
US9585915B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 22, 2015 |
| Grant date | Mar 7, 2017 |
| Priority date | — |
| Expiry date | Jan 22, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to compositions comprising a recombinant polypeptide comprising a cell signaling sequence, e.g., JAG-1 sequence, fused to a hydrogel polypeptide sequence. In certain embodiments, the disclosure relates to methods of cell culture on three dimensional scaffolds/hydrogels composed of self-assembling peptides disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.