Patent · US Active

Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy

US9586945B2 · kind B2 · utility

0Cited by

30References

21Claims

0Family size

Assignees

Abb Vie Deutschland Gmbh & Co. KG · DE
Abb Vie Inc. · US

Inventors

Wilhelm Amberg · Ludwigshafen, DE
Frauke Pohlki · Wiesbaden, DE
Udo Lange · Ludwigshafen, DE
Ying Wang · Lake Villa, US
Jason T. Brewer · Zion, US
Anil Vasudevan · Union Grove, US
Yanbin Lao · Libertyville, US
Charles W. Hutchins · Libertyville, US
Hongyu Zhao · Libertyville, US
Huan-Qiu Li · Cambridge, US

Key dates

Filing date	Oct 17, 2014
Grant date	Mar 7, 2017
Priority date	—
Expiry date	Oct 17, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.