Patent · US Active

Glycan-modified anti-CD4 antibody with improved HIV-1 neutralizing activity

US9587022B2 · kind B2 · utility

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1References

2Claims

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Assignee

The Rockefeller University · US

Inventors

Ruijiang Song · New York, US
David D. Ho · Kaohsiung, TW

Key dates

Filing date	Dec 18, 2013
Grant date	Mar 7, 2017
Priority date	—
Expiry date	Dec 18, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are glycan-modified anti-CD4 monoclonal antibodies with N-linked glycans attached to the variable region. Expression vectors and cell lines useful for the production of such antibodies, and use of such antibodies for HIV prevention and therapy are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.