Determination of tissue oxygenation in vivo

US9591999B2 · kind B2 · utility

Assignee

• University of Washington through its Center for Commercialization · US

Inventors

• Kenneth Schenkman · Seattle, US
• Lorilee Arakaki · Bainbridge Island, US
• Wayne Ciesielski · Seattle, US
• Jeremy Martin Shaver · Lake Forest Park, US

Key dates

• Filing date: Nov 3, 2011
• Grant date: Mar 14, 2017
• Expiry date: Apr 5, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2562/043
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the NIR light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.