Patent · US Active

Complete human skin organ generated from culture-expanded cells

US9592257B2 · kind B2 · utility

7Cited by
0References
20Claims
0Family size

Inventors

Key dates

Filing dateOct 14, 2014
Grant dateMar 14, 2017
Priority date—
Expiry dateOct 14, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N5/0698
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Systems and methods can support generation of a full-thickness, human skin organ from tissue culture expanded cells. Human dermal and epidermal progenitor cells can be isolated from human tissues. Isolated cells may be cultured as epidermal cells while other isolated cells may be separately cultured as dermal cells. The cultured epidermal cells and dermal cells may be combined for co-culturing. The co-cultured cells may be suspended within a slurry. The co-cultured cells may be implanted onto a recipient organism for generation of a full-thickness skin organ comprising fully cycling hair follicles, adipose tissue, and other skin organ structures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.