Patent · US Active

Modified apelin polypeptides

US9593153B2 · kind B2 · utility

0Cited by

0References

5Claims

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Assignees

INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) · FR
UNIVERSITÉ PARIS CITÉ · FR
UNIVERSITÉ DE BORDEAUX · FR

Inventors

Géraldine SIEGFRIED · Blois, FR
Abdel-Majid Khatib · Pessac, FR

Key dates

Filing date	Apr 9, 2013
Grant date	Mar 14, 2017
Priority date	—
Expiry date	Apr 9, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/47
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to polypeptides and their uses as apelin inhibitors. More particularly, the present invention relates to a polypeptide comprising the sequence as set forth in SEQ ID NO:1 wherein at least one arginine residue at position 18, 19, 22 or 23 has been substituted or deleted.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.