Media for culturing, preserving, and administering regenerative cells

US9593309B2 · kind B2 · utility

Assignees

• ARTHRODYNAMIC HOLDINGS, LLC · US
• INGENERON, INC. · US

Inventors

• Michael E. Coleman · Pompano Beach, US
• Ivone Bruno · Houston, US
• Rudy Martinez · Houston, US
• Amir Sanchez · Houston, US
• Eckhard Alt · Ottobrunn, DE
• Frank D. Marcum · Lexington, US
• Paul Shealy · Savannah, US

Key dates

• Filing date: May 8, 2015
• Grant date: Mar 14, 2017
• Expiry date: May 8, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2539/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A culture media, media supplement, or soluble matrix for cryopreservation or enhanced regenerative cell growth in culture and maintenance of multi-lineage differentiation potentiation. The inventive culture media, media supplement, or soluble matrix comprises a GAG composition comprising a sulfated GAG, such as chondroitin sulfate. A soluble matrix, a cell administration package or kit comprising the soluble matrix and a device for cell administration, and a method of use thereof, for administration of regenerative cells for treating a joint disease or other weakened or damaged tissue comprising the specified GAG compositions are further provided.