Methods and models for assessing anti-aging benefits of agents
US9593363B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 17, 2013 |
| Grant date | Mar 14, 2017 |
| Priority date | — |
| Expiry date | Jun 17, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A screening method for identifying an agent as effective for providing an anti-aging skin benefit is provided. The screening method includes culturing first and second human skin samples from about 3 days to about 19 days, wherein the first and second human skin samples are derived from a human skin surgical waste tissue. The first human skin sample is contacted with at least one test agent. The second human skin sample is contacted with a positive control. Transcriptional profiles are generated from the first and second human skin samples, and the at least one test agent is identified as effective for providing an anti-aging skin benefit when the transcriptional profiles of at least two genes show a similar directional change in comparison to one or more untreated control tissue samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.