Patent · US Active

Test solvent for evaluating the compatibility of biologically active substances and graft copolymers

US9594073B2 · kind B2 · utility

0Cited by

3References

13Claims

0Family size

Assignee

Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

Jorg Breitenbach · Mannheim, DE
Bernd Liepold · Dossenheim, DE
Jürgen Weis · Frankfurt am Main, DE

Key dates

Filing date	Feb 15, 2011
Grant date	Mar 14, 2017
Priority date	—
Expiry date	Jul 8, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08F283/06
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A liquid mixture, comprising a) at least one compound selected from polyols, polyol ethers wherein at least one hydroxyl group is unetherified, or polyalkylene ethers wherein at least one terminal hydroxyl group is unetherified, b) 1,3-bis(caprolactam-1-yl) butane, and c) diacetoxybutane mimics the solubility properties of a graft copolymer comprising a poly(alkylene glycol) backbone and a vinyl acetate/N-vinylcaprolactam copolymer grafted onto the backbone. In a method for evaluating the compatibility of a biologically active substance with the graft copolymer i) the biologically active sub-stance is brought into contact with the liquid mixture, and ii) the phase behavior of the test system and/or the solubility of the biologically active substance in the mixture is determined.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.