Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis
US9595089B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 17, 2015 |
| Grant date | Mar 14, 2017 |
| Priority date | — |
| Expiry date | Apr 25, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30104
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and system for non-invasive hemodynamic assessment of coronary artery stenosis based on medical image data is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient. Patient-specific boundary conditions of a computational model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements of the coronary arteries. Blood flow and pressure in the coronary arteries are simulated using the computational model of coronary circulation and the patient-specific boundary conditions and coronary autoregulation is modeled during the simulation of blood flow and pressure in the coronary arteries. A wave-free period is identified in a simulated cardiac cycle, and an instantaneous wave-Free Ratio (iFR) value is calculated for a stenosis region based on simulated pressure values in the wave-free period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.