Injectable delivery system for heparan-binding growth factors
US9597412B2 · kind B2 · utility
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7References
14Claims
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Key dates
| Filing date | Mar 16, 2012 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Sep 29, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.