Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
US9598396B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Aug 18, 2015 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Aug 18, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D221/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, R7 and Y have defined meanings.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.