Patent · US Active

Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer

US9598416B2 · kind B2 · utility

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0References

7Claims

0Family size

Assignee

Bayer Intellectual Property GmbH · DE

Inventors

Marie-Pierre Collin · Wuppertal, DE
Dirk Brohm · Mettmann, DE
Melanie HEROULT · Mülheim an der Ruhr, DE
Mario Lobell · Wuppertal, DE
Walter Hubsch · Wuppertal, DE
Klemens Lustig · Wuppertal, DE
Sylvia Grünewald · Berlin, DE
Ulf Bömer · Glienicke, DE
Verena Vöhringer · Wuppertal, DE
Niels Lindner · Wuppertal, DE

Key dates

Filing date	Dec 11, 2012
Grant date	Mar 21, 2017
Priority date	—
Expiry date	Dec 11, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-fJ[1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.