Antigen binding formats for use in therapeutic treatments or diagnostic assays
US9598499B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Dec 29, 2011 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Feb 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to antigen binding formats for use in therapeutic treatments or diagnostic assays. The present invention relates to an antigen-binding format consisting of: —a first fusion protein wherein the CH1 constant domain of an antibody is fused i) by its N-terminal end to the C-terminal end of a variable domain of an antibody and ii) by its C-terminal end to the N-terminal end of a variable domain of an antibody and, —a second fusion protein wherein the CL constant domain of an antibody is fused by its N-terminal end to the C-terminal end of a variable domain of an antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.