Use of Galerina marginata genes and proteins for peptide production
US9598686B2 · kind B2 · utility
1Cited by
5References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 5, 2015 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Nov 5, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21026
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.