Methods for processing coagulation factors
US9598687B2 · kind B2 · utility
1Cited by
2References
28Claims
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Key dates
| Filing date | Aug 31, 2012 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Jun 13, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/647
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present application relates to methods for purifying recombinant coagulation factor proteins, including for example, prothrombin (Factor II). In embodiments, the methods provide purified prothrombin that exhibit increased bioactivity and reduced levels of thrombin, thereby increasing the safety of the prothrombin. Also provided are purified recombinant coagulation factor proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.