Cartridge for performing assays in a closed sample preparation and reaction system
US9598722B2 · kind B2 · utility
23Cited by
357References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 11, 2014 |
| Grant date | Mar 21, 2017 |
| Priority date | — |
| Expiry date | Apr 1, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0683
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.