Anti-cancer polyketide compounds

US9604973B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Michael D. Burkart · Boston, US
• James J. La Clair · San Diego, US
• Brian D. Jones · Brookline, US
• Alexander Laurence Mandel · Vancouver, CA
• Reymundo Villa · San Mateo, US
• Januario E. Castro · San Diego, US
• Manoj Kumar Kashyap · San Diego, US
• Deepak Kumar · Delhi, IN

Key dates

• Filing date: Sep 26, 2014
• Grant date: Mar 28, 2017
• Expiry date: Sep 26, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D313/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided herein, inter alia, are anticancer polyketides. The uses of the polyketides described herein include treatment of cancer, for example, through regulation of the spliceosome and detection of spliceosome inhibition.