Cyclic thienouracil-carboxamides and use thereof

US9604996B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Michael Härter · Wixom, US
• Martina Delbeck · Essen, DE
• Bernd Kalthof · Wuppertal, DE
• Klemens Lustig · Wuppertal, DE
• Niels Lindner · Wuppertal, DE
• Raimund Kast · Wuppertal, DE
• Pierre Wasnaire · Mülheim an der Ruhr, DE
• Frank Sü;meier · Munich, DE

Key dates

• Filing date: Oct 2, 2014
• Grant date: Mar 28, 2017
• Expiry date: Oct 2, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.