Pressure driven microfluidic injection for chemical separations

US9606082B2 · kind B2 · utility

Assignee

• The University of North Carolina at Chapel Hill · US

Inventors

• John Scott Mellors · Carrboro, US
• Erin Anne Redman · Carrboro, US
• John Michael Ramsey · Chapel Hill, US

Key dates

• Filing date: Jan 4, 2016
• Grant date: Mar 28, 2017
• Expiry date: Jan 4, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/167
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods are particularly suitable for use with a mass spectrometer.