Anti-DR5 family antibodies, bispecific or multivalent anti-DR5 family antibodies and methods of use thereof

US9611327B2 · kind B2 · utility

Assignee

• GENMAB B.V. · NL

Inventors

• Claudine Vermot-Desroches · Dardilly, FR
• Olivier Frédéric Subiger · Belleville, FR
• Laurence Françoise Jeanne-Marie Bourdin · Écully, FR

Key dates

• Filing date: Jul 9, 2013
• Grant date: Apr 4, 2017
• Expiry date: Oct 31, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/75
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Anti-DR5 family member antibodies and bispecific antibodies comprising one or more anti-DR5 family member antibodies are disclosed. These antibodies can be used to trigger cell death on DR5 positive cells.