Active protease-resistant antibody FC mutants
US9611328B2 · kind B2 · utility
0Cited by
7References
12Claims
0Family size
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Key dates
| Filing date | Sep 22, 2014 |
| Grant date | Apr 4, 2017 |
| Priority date | — |
| Expiry date | Sep 22, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to modified Fc-containing molecules including modified antibodies characterized by increased resistance to host and pathogen-derived proteases, ability to interact with FcγR receptors except with FcγRI, and lack of induction of IL-10 secretion by macrophages, and methods of using and making them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.