Method for producing soluble recombinant interferon protein without denaturing
US9611499B2 · kind B2 · utility
0Cited by
37References
28Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 15, 2015 |
| Grant date | Apr 4, 2017 |
| Priority date | — |
| Expiry date | Oct 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.