RSV antiviral compounds

US9617289B2 · kind B2 · utility

Assignee

• Janssen Sciences Ireland UC · IE

Inventors

• Abdellah Tahri · Anderlecht, BE
• Sandrine Marie Helene Vendeville · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe, BE
• Tim Hugo Maria Jonckers · Heist-op-den-Berg, BE
• Pierre Jean-Marie Bernard Raboisson · Sligo, IE
• Lili Hu · Mechelen, BE
• Samuël Dominique Demin · Ekeren, BE
• Ludwig Paul Cooymans · Beerse, BE

Key dates

• Filing date: Oct 15, 2013
• Grant date: Apr 11, 2017
• Expiry date: Oct 15, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Inhibitors of RSV replication of formula RIincluding stereochemically isomeric forms, and salts or solvates thereof, wherein R22, W, Q, V, Z p, s, and Het have the meaning as defined herein.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other RSV inhibitors, in RSV therapy.