Vascular model, method for producing said model and use thereof

US9618500B2 · kind B2 · utility

Assignee

• KARLSRUHER INSTITUT FÜR TECHNOLOGIE · DE

Inventors

• Stefan Giselbrecht · Karlsruhe, DE
• Isabella Hebeiss · Widdern, DE
• Ute Schepers · Troisdorf, DE
• Roman Truckenmueller · Flein, DE

Key dates

• Filing date: Jun 24, 2013
• Grant date: Apr 11, 2017
• Expiry date: Oct 28, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12M29/26
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A vascular model includes at least one microchannel perfusable by at least one fluid and in a form of a hollow structure having a wall thickness in a range from 0.1 μm to 1000 μm, a concave inner surface with a cross-section which is circular in part and at least one pore having a diameter in a range from 1 nm to 100 μm. The at least one microchannel has a width in a range from 0.01 μm to 10 mm and a depth in a range from 0.01 μm to 10 mm. At least one chamber is perfusable by a same and/or different fluid and surrounds the at least one microchannel over an entire length and width or over parts thereof. The at least one chamber adjoins the at least one microchannel. At least one connector is configured to receive and/or discharge the at least one fluid.