Chitosan hydrogel for repairing nerve tissue
US9623044B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 16, 2013 |
| Grant date | Apr 18, 2017 |
| Priority date | — |
| Expiry date | Jul 16, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to chitosan hydrogel microparticles of a median size d50 comprised between 1 and 500 μm (obtained from a number distribution), the chitosan having a degree of acetylation of less than equal to 20% and its concentration in the hydrogel being comprised between 0.25 and 5% by weight based on a total weight of the hydrogel, for use in neuron regeneration and/or in the repair of the nervous system, advantageously of the central nervous system, and/or in the grafting of neurons and/or in the treatment of neurodegenerative diseases and/or in the treatment of paralyses.It also relates to an implant comprising an aqueous suspension of microparticles mixed with Schwann cells and/or stem cells and/or trophic factors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.