Devices and methods for molecular diagnostic testing

US9623415B2 · kind B2 · utility

Assignee

• Click Diagnostics, Inc. · US

Inventors

• Boris ANDREYEV · Foster City, US
• Keith Moravick · Mountain View, US
• Brian CIOPYK · Santa Clara, US
• Victor Briones · Gilroy, US
• Gregory Loney · Los Altos, US
• Adam DE LA ZERDA · Los Altos, US
• Jesus Ching · Saratoga, US
• Colin Kelly · Midvale, US
• Steven Chu · Menlo Park, US
• David Swenson · Santa Clara, US
• Helen HUANG · San Pablo, US

Key dates

• Filing date: Dec 30, 2015
• Grant date: Apr 18, 2017
• Expiry date: Dec 30, 2035

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0644
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.