Therapeutic piperazines
US9624200B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2014 |
| Grant date | Apr 18, 2017 |
| Priority date | — |
| Expiry date | Oct 25, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention includes a compound of formula I:wherein R1, Y, A, n, R4 and Z have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of PDE4 function and are useful for improving cognitive function and/or treating cognitive disorders or impairment, traumatic and/or ischemic injuries of the central and peripheral nervous system and/or psychiatric disorders in animals, especially humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.