Mutated structural protein of a parvovirus

US9624274B2 · kind B2 · utility

Assignees

• Medi&Gene Inc. · DE
• Ludwig-Maximilians-Universitat Munchen · DE
• UNIVERSITAET ZU KOELN · DE

Inventors

• Kerstin Lux · Munich, DE
• Hildegard BUENING · Cologne, DE
• John Nieland · Munich, DE
• Jorge Boucas · Cologne, DE
• Mirko Ritter · Bernried, DE
• Markus Hoerer · Planegg, DE
• Luca Perabo · Cologne, DE
• Michael Hallek · Cologne, DE

Key dates

• Filing date: Oct 11, 2012
• Grant date: Apr 18, 2017
• Expiry date: Oct 11, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2810/405
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is related to a structural protein of a parvovirus with an amino acid insertion at the insertion site I-453, a library comprising the protein, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a vector, virus, or cell comprising the nucleic acid, a process for the preparation of the protein, a medicament comprising the protein, nucleic acid, or multimeric structure as well as methods and uses involving the protein, nucleic acid, or multimeric structure.