Optimization of nucleation and crystallization for lyophilization using gap freezing
US9625210B2 · kind B2 · utility
3Cited by
20References
20Claims
0Family size
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Key dates
| Filing date | Nov 17, 2014 |
| Grant date | Apr 18, 2017 |
| Priority date | — |
| Expiry date | Dec 9, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/68
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously and at approximately the same rate. The as frozen solution can then provide a lyophilized cake of the solutes with large and uniform pores.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.