Patent · US Active

Method for diagnosing alzheimer's disease (AD)

US9625459B2 · kind B2 · utility

1Cited by

0References

18Claims

0Family size

Assignee

AFFIRIS AG · AT

Inventors

Guenther Staffler · Wien, AT
Andreas Mairhofer · Wien, AT
Achim Schneeberger · Fort Lauderdale, US
Martina Lutterova · Bratislava, SK
Walter Schmidt · Wien, AT
Frank Mattner · Wien, AT

Key dates

Filing date	Sep 20, 2012
Grant date	Apr 18, 2017
Priority date	—
Expiry date	Sep 20, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2821
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Disclosed is a method for diagnosing Alzheimer's disease (AD) wherein Aβ-specific antibodies in a biological sample of a person that is suspected of having AD are detected comprising the following steps: —contacting the sample with Aβ-aggregates or with particles having Aβ-aggregate like surfaces and allowing the Aβ-specific antibodies to bind to the Aβ-aggregates, and —detecting the Aβ-specific antibodies bound to the Aβ-aggregates by a single particle detection technique, preferably by fluorescence activated cell sorting (FACS); and wherein the amount of Aβ-specific antibodies detected is compared with the amount in a sample of known AD status.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.