Non-contact infrared thermocycling
US9630182B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Dec 4, 2013 |
| Grant date | Apr 25, 2017 |
| Priority date | — |
| Expiry date | Feb 11, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/1894
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A microfluidic chip includes one or more reaction chambers to hold fluids for chemical or biochemical reactions, such as PCR. A non-contact heat source heats the reaction chamber and the fluid, such that the heat source does not contact the reaction chamber or the fluid. The heat source can heat the reaction chamber and the fluid separately, where the reaction chamber and the fluid separately absorb heat radiation from the heat source. A temperature sensor acquires a temperature of the reaction chamber and/or the fluid. Control circuitry controls the heat source according to a cycling profile for the reaction in the fluid to cycle the heat source between heating and not heating the reaction chamber and the fluid based on the temperature acquired by the temperature sensor. Cooling can be provided passively or actively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.