HER2Delta16 peptides
US9630993B2 · kind B2 · utility
3Cited by
3References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 14, 2015 |
| Grant date | Apr 25, 2017 |
| Priority date | — |
| Expiry date | May 14, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides cyclic peptides comprising a dimer of peptides, each peptide comprising a sequence corresponding to the HER2 splice variant HER2Delta16, wherein the cyclic peptide is cyclized via a disulfide bond between the peptides and via an amino acid linking the peptides. The invention also provides methods of making antibodies that specifically bind to HER2Delta16 homodimers using said cyclic peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.