Multispecific antigens binding fragments and multispecific antibodies derived therefrom comprising mutant CH1 and CL-κ domains
US9631031B2 · kind B2 · utility
3Cited by
1References
7Claims
0Family size
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Key dates
| Filing date | Jul 6, 2012 |
| Grant date | Apr 25, 2017 |
| Priority date | — |
| Expiry date | Mar 1, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/732
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy/light chain mispairing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.