Gene cluster for biosynthesis of cornexistin and hydroxycornexistin

US9631212B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Oskar Zelder · Speyer, DE
• Birgit Hoff · Ludwigshafen, DE
• Hartwig Schroeder · Greytown, ZA
• Andrea Molt · Weinheim, DE
• Holger Hartmann · Ludwigshafen, DE
• Klaus Ditrich · Neheim, DE
• Michael Breuer · Darmstadt, DE
• Rüdiger Reingrubber · Ludwigshafen, DE
• Jakob Weber · Bad Liebenzell, DE

Key dates

• Filing date: Nov 13, 2013
• Grant date: Apr 25, 2017
• Expiry date: Nov 13, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P17/04
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.