Rapid antibiotic susceptibility testing

US9632085B2 · kind B2 · utility

Assignee

• President and Fellows of Harvard College · US

Inventors

• Michael Super · Lexington, US
• Donald E. Ingber · Boston, US
• Mark J. Cartwright · Newton, US
• Alexander L. Watters · Melrose, US
• John Samuel Workman · Seattle, US
• Daniel Levner · Brookline, US
• Martin Rottman · La Celle-Saint-Cloud, FR

Key dates

• Filing date: Feb 28, 2013
• Grant date: Apr 25, 2017
• Expiry date: Feb 28, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A90/10
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Embodiments of various aspects described herein are directed to methods, compositions, kits and systems for rapid determination of antibiotic susceptibility of a microbe within hours after a sample is collected. In some embodiments, the methods, compositions, kits and systems described herein can allow determination of antibiotic susceptibility of a microbe based on a small number of microbes, e.g., as few as 5-10 microbes bound to a microbe-targeting substrate described herein.